The 13th Conference on Arti?cial Intelligence: Methodology, Systems, App- cations (AIMSA 2008) was held in Varna, Bulgaria, on September 4-6, 2008. The AIMSA conference series has provideda biennial forum for the presentation of arti?cial intelligence research and development since 1984. The conference covered the full range of topics in arti?cial intelligence and related disciplines and provided an ideal forum for international scienti?c exchange between C- tral/Eastern Europe and the rest of the world. For AIMSA 2008, wedecided to placespecial emphasisonthe worksonth- ries, experimentations, applications, and case studies that demonstrate in pr- tice the added value and the impact ofAI science, methodologiesand techniques for the market, society, and culture. We believe that this vision of "AI@WORK" truly re?ects the original intention of AIMSA, a conference dedicated to ar- cial intelligence in its entirety but with a special emphasis on "methodology, systems, and applications", as explicitly stated in its name. According to this vision, we have also paid special attention to works that "cross the boundaries of AI", i. e., works that demonstrate the in?uence of AI on di?erent ?elds of research and di?erent scienti?c communities, such as software engineering, data bases, distributed systems, information systems, information retrieval, etc. Both of these aspects were covered by the papers that were submitted and by those that were accepted for publication. A total of 109 papers were submitted to the conference, and the program committee accepted 30 full papers and 10 posters.